Viral RNA Extraction

Reagent Kits: RNAdvance Viral or RNAdvance Viral XP

Extract high-quality RNA from Saliva or Swab Transport Media samples using SPRI paramagnetic bead-based technology. Our viral RNA extraction kits are available for your unique input sample types and collection devices. RNAdvance Viral XP offers higher throughput capabilities and the RNAdvance Viral kit is optimal for extracting from a variety of challenging sample inputs.

• Produces high-integrity viral RNA for use with PCR-based applications for infectious disease and pathogen research
• Performance Limit of Detection (LoD) demonstrated at 1 copy/uL for viral RNA
• Automation-ready, viral extraction quickly adapted to liquid handling platforms

RNAdvance Viral XP is listed as an extraction method for use with the Centers for Disease Control’s EUA-authorized COVID-19 test referenced in FDA’s FAQ on testing for SARS-CoV-2. Other than this designation, RNAdvance Viral XP is for research use, and not intended for diagnostic purposes.

RNA Extraction from Cells

RNAdvance Cell v2

Reliably extract RNA from cells without the need for filtration or centrifugation.

• Consistently delivers a high yield of pure nucleic acids
• Produces high-integrity RNA for NGS and other PCR-based applications
• Suitable for manual or automated processing

 

 

RNA Extraction from FFPE Tissue

FormaPure XL RNA

With our SPRI paramagnetic bead-based chemistry, you can extract RNA from even the most challenging formalin-fixed paraffin-embedded (FFPE) tissue samples.

For optimum convenience, you receive knowledgeable support for reagents and automation methods from a single vendor.

• Fragment analysis shows FormaPure XL RNA kits isolate RNA with the best possible integrity—even from 10+-year-old tissue blocks
• Performance demonstrated with a variety of sample and tissue types
• Scalable based on throughput
• Demonstrated performance with 7x 10 μM curls

 

 

RNA Extraction from Tissue

RNAdvance Tissue

Extract RNA from a wide variety of tissues without the waste-removal hazards of organic solvents.

• Produces high recovery of total RNA from soft, fibrous and lipid-rich tissues
• Generates high-quality and high-integrity RNA to help optimize downstream applications
• Automation-friendly

 

 

Cell-Free DNA Extraction from Plasma

Apostle MiniMax™ High Efficiency Isolation Kit

Extraction of cell-free DNA (cfDNA) from plasma, serum, and urine using magnetic bead-based technology.

• Extraction of cfDNA from up to 5 mL of liquid input
• Demonstrated capability with NGS and PCR-based assays
• Demonstrated extraction from cell-free DNA collection tubes

 

 

DNA Extraction from Blood

GenFind V3

Extraction and purification of genomic DNA (gDNA) from whole blood using Solid Phase Reversible Immobilization (SPRI) paramagnetic bead-based technology.

• Consistently and optimal purity and quality of gDNA isolates
• No carryover of inhibitors from anticoagulants, for exceptional PCR-based applications and NGS

 

 

 

DNA Extraction from FFPE Tissue

FormaPure XL DNA

Use our SPRI paramagnetic bead-based chemistry for efficient and consistent extraction of DNA from formalin-fixed paraffin-embedded tissues.

• Performance demonstrated with a variety of sample and tissue types
• Demonstrated performance with 7x 10 μM curls

 

 

 

DNA Extraction from Tissue

DNAdvance

A high-throughput genomic DNA (gDNA) extraction reagent kit that enables purification of high-quality DNA from mammalian tissue samples.

• Compatible with a variety of downstream analysis tools (e.g., PCR, qPCR, SNP genotyping and NGS)
• Manual and automation-friendly chemistry
• Process three 96-well plates in ~1 hour using automation

 

 

 

DNA Plasmid Purification

CosMCPrep

A SPRI paramagnetic bead-based system for all your plasmid purification needs.

• Use a single protocol to purify a variety of high- and low-copy number template types
• Perform manually or automated without sacrificing product quality
• Purify plasmids in a 96-well format for high-throughput sample processing

 

 

 

AMPure XP for PCR Purification

Cleanup and Size Selection

You can use our proprietary SPRI paramagnetic bead-based chemistry to remove contaminants (dNTPs, salts, primers, primer dimers) throughout your NGS workflows.

• Used in a variety of NGS library prep chemistries
• Compatible with manual and automated processing
• High recovery of amplicons > 100 bp
• Predictable and consistent size selection

 

 

RNA and cDNA Cleanup

RNAClean XP

Purify RNA and cDNA from common enzymatic reactions using our proprietary SPRI paramagnetic bead-based chemistry.

• Compatible with manual and automated processing
• Complete removal of salts, unincorporated primers and dNTPs
• Used in RNA-Seq library preparations
• Certified RNAse-free

 

 

Sanger Dye Terminator Removal

CleanSEQ Cleanup and Size Selection

A rapid, high-performance dye-terminator removal process using a paramagnetic bead-based technology.

• Requires no centrifugation or filtration
• Performed manually or fully automated for high-throughput dye-terminator removal
• Produces sequences with longer Phred 20 read lengths and higher signal intensities than any other purification technology

 

 

 

SPRIselect for Size Selection

Purify DNA fragments of the desired size for library preparation using our proprietary SPRI paramagnetic bead-based chemistry, which provides:

• Tunable fragment size selection to suit specific applications
• Predictable, consistent size selection between runs and reagent lots
• Compatibility with manual and automated processing